Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3298254 | 0.81 | KMT2A (0.54) | MEN1KMT2ARAB9ACASP6MAPT | |
| SCHEMBL8568311 | 0.80 | ALOX15 (0.53) | MEN1KMT2ARAB9ACASP6MAPT | |
| SCHEMBL483953 | 0.79 | CTSB (0.50) | MEN1KMT2ARAB9ACASP6MAPT | |
| SCHEMBL6272457 | 0.79 | ALDH1A1 (0.66) | MEN1KMT2ARAB9AMAPTMAPK1 | |
| SCHEMBL28232869 | 0.79 | ALDH1A1 (0.66) | MEN1KMT2ARAB9AMAPTMAPK1 | |
| SCHEMBL8561151 | 0.79 | BACE1 (0.51) | MEN1KMT2ARAB9ACASP6MAPT | |
| SCHEMBL8562475 | 0.79 | KMT2A (0.49) | MEN1KMT2ARAB9ACASP6MAPT | |
| SCHEMBL2137910 | 0.79 | MAPT (0.52) | MEN1KMT2ARAB9ACASP6MAPT | |
| SCHEMBL2136947 | 0.78 | MAPT (0.57) | MEN1KMT2ARAB9AMAPTMAPK1 | |
| SCHEMBL27795495 | 0.78 | ALDH1A1 (0.64) | MEN1KMT2ARAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |