Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GCK | P35557 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28368341 | 0.85 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1TDP1PKMGCK | |
| SCHEMBL8568267 | 0.82 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1TDP1PKMGCK | |
| SCHEMBL8568262 | 0.77 | ALDH1A1 (0.74) | ALDH1A1TDP1MAPK8KMT2AGAA | |
| SCHEMBL10699924 | 0.74 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TDP1PKMKMT2A | |
| SCHEMBL351842 | 0.73 | ITGB1 (0.40) | ALDH1A1L3MBTL1GAAKDM4E | |
| SCHEMBL10666285 | 0.72 | KMT2A (0.45) | ALDH1A1L3MBTL1TDP1KMT2AMAPT | |
| SCHEMBL18681347 | 0.71 | BRAF (0.70) | GCKBRAFKDR | |
| SCHEMBL7454922 | 0.70 | ALDH1A1 (0.40) | ALDH1A1KMT2AGAAMAPTKDM4E | |
| SCHEMBL20704159 | 0.70 | MEN1 (0.44) | ALDH1A1L3MBTL1TDP1MAPK8KMT2A | |
| SCHEMBL11472877 | 0.70 | KDM4E (0.51) | L3MBTL1TDP1KMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |