Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28368341 | 0.88 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1TDP1PKMMAPK8 | |
| SCHEMBL8566558 | 0.82 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1TDP1RAB9APKM | |
| SCHEMBL7512439 | 0.81 | PARP10 (0.48) | ALDH1A1PARP10RAB9AMAPK8MEN1 | |
| SCHEMBL28752345 | 0.80 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TDP1PARP10RAB9A | |
| SCHEMBL3661678 | 0.79 | SIRT2 (0.47) | ALDH1A1TDP1MAPK8KDM4EMAPK10 | |
| SCHEMBL14353384 | 0.79 | POLB (0.54) | L3MBTL1TDP1PARP10KDM4ENTRK1 | |
| SCHEMBL4558531 | 0.78 | S1PR3 (0.46) | ALDH1A1L3MBTL1TDP1PARP10RAB9A | |
| SCHEMBL10699924 | 0.76 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TDP1RAB9APKM | |
| SCHEMBL27958077 | 0.76 | NOS3 (0.47) | ALDH1A1L3MBTL1TDP1RAB9AMEN1 | |
| SCHEMBL8476094 | 0.74 | ALDH1A1 (0.51) | ALDH1A1TDP1PARP10RAB9ACTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |