Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570338 | 0.88 | CHRM2 (0.45) | OPRM1OPRK1OPRD1OGFRL1SLC18A3 | |
| SCHEMBL6164725 | 0.84 | CHRM3 (0.50) | OPRM1OPRK1OPRD1OPRL1CHRM3 | |
| SCHEMBL8564042 | 0.84 | CHRM2 (0.43) | CYP2D6CHRM2CHRM3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6166889 | 0.83 | CHRM3 (0.49) | OPRM1OPRK1OPRD1OPRL1CHRM3 | |
| SCHEMBL5103372 | 0.81 | SLC18A3 (0.40) | OPRD1SLC18A3ALDH1A1 | |
| SCHEMBL6168606 | 0.81 | OPRL1 (0.52) | OPRM1OPRK1OPRL1CYP2D6CYP2C19 | |
| SCHEMBL29445321 | 0.81 | OPRL1 (0.52) | OPRM1OPRK1OPRL1CYP2D6CYP2C19 | |
| SCHEMBL8564971 | 0.81 | TACR1 (0.43) | OPRM1OPRK1OPRL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8571208 | 0.80 | KDM1A (0.40) | OPRD1SLC18A3ALDH1A1 | |
| SCHEMBL6168102 | 0.80 | CHRM3 (0.42) | OPRM1OPRK1OPRD1OPRL1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |