Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.38 |
| ▸ | PDE6D | O43924 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445321 | 0.88 | OPRL1 (0.52) | OPRL1OPRM1OPRK1MEN1KMT2A | |
| SCHEMBL6168606 | 0.88 | OPRL1 (0.52) | OPRL1OPRM1OPRK1MEN1KMT2A | |
| SCHEMBL6168284 | 0.87 | TACR1 (0.41) | TACR1OPRL1OPRM1PDE6DMEN1 | |
| SCHEMBL6168102 | 0.87 | CHRM3 (0.42) | TACR1OPRL1OPRM1PRKCGPRKCB | |
| SCHEMBL8564042 | 0.86 | CHRM2 (0.43) | TACR1PRCPALDH1A1MEN1KMT2A | |
| SCHEMBL8565908 | 0.86 | TACR1 (0.41) | TACR1OPRL1ALDH1A1MEN1KMT2A | |
| SCHEMBL8567952 | 0.86 | SLC18A3 (0.49) | TACR1OPRL1OPRM1PDE6D | |
| SCHEMBL8568996 | 0.85 | KDM1A (0.49) | TACR1PDE6DMEN1KMT2ADRD2 | |
| SCHEMBL8571710 | 0.85 | PRCP (0.42) | TACR1OPRL1PRCPPDE6DALDH1A1 | |
| SCHEMBL8571012 | 0.85 | CHRM2 (0.49) | OPRL1MEN1KMT2ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |