Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6369444 | 0.85 | ALOX15 (0.45) | NOS2ALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL22897758 | 0.84 | TDP1 (0.48) | NOS2ALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL10854027 | 0.82 | NOS2 (0.42) | NOS2ALDH1A1TP53SLC6A4SLC6A2 | |
| SCHEMBL4854098 | 0.81 | TYR (0.50) | NOS2ALDH1A1ALOX15HSD17B10TDP1 | |
| SCHEMBL3634469 | 0.80 | KDM4E (0.45) | NOS2ALDH1A1TDP1TP53SLC6A4 | |
| SCHEMBL2889115 | 0.75 | ALOX15 (0.52) | ALDH1A1ALOX15HSD17B10TDP1CYP3A4 | |
| SCHEMBL4001757 | 0.74 | ALOX15 (0.56) | ALDH1A1ALOX15HSD17B10TDP1CYP3A4 | |
| SCHEMBL30316721 | 0.74 | ALOX15 (0.56) | ALDH1A1ALOX15HSD17B10TDP1CYP3A4 | |
| SCHEMBL5032198 | 0.74 | ALOX15 (0.56) | ALDH1A1ALOX15HSD17B10TDP1CYP3A4 | |
| SCHEMBL29617187 | 0.74 | ALOX15 (0.56) | ALDH1A1ALOX15HSD17B10TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429614-B1 | AZOPHENYL COMPOUNDS | JAMES ROBINSON LTD (GB) | 1995-10-11 | — | — | EP | claimed |
| WO-1990015850-A1 | AZOPHENYL COMPOUNDS | JAMES ROBINSON LIMITED (GB) | 1990-12-27 | — | — | WO | claimed |
| US-5719270-A | DYES, INTERMEDIATES | PARTINGTON STEVEN MICHAEL (GB) | 1998-02-17 | — | — | US | disclosed |
| EP-0429614-B1 | AZOPHENYL COMPOUNDS | JAMES ROBINSON LTD (GB) | 1995-10-11 | — | — | EP | disclosed |
| WO-1990015850-A1 | AZOPHENYL COMPOUNDS | JAMES ROBINSON LIMITED (GB) | 1990-12-27 | — | — | WO | disclosed |