Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | DDX3X | O00571 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566834 | 1.00 | KMT2A (0.58) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL27470350 | 0.85 | ALDH1A1 (0.62) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL27582546 | 0.82 | KMT2A (0.67) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL10692848 | 0.81 | KMT2A (0.66) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL27964933 | 0.77 | KMT2A (0.69) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL3207627 | 0.77 | KMT2A (0.78) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL6069337 | 0.77 | ALDH1A1 (0.69) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL20474540 | 0.77 | KMT2A (0.60) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL11503152 | 0.77 | KMT2A (0.63) | KMT2AMEN1MAPTPOLBDDX3X | |
| SCHEMBL31185157 | 0.76 | SMN1; SMN2 (0.68) | KMT2AMEN1MAPTPOLBDDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |