Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.47 |
| ▸ | CNR1 | P21554 | 4/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569219 | 1.00 | CNR2 (0.47) | CNR2CNR1FAAHPTPN11S1PR3 | |
| SCHEMBL8567786 | 1.00 | CNR2 (0.47) | CNR2CNR1FAAHPTPN11S1PR3 | |
| SCHEMBL8572650 | 1.00 | CNR2 (0.47) | CNR2CNR1FAAHPTPN11S1PR3 | |
| SCHEMBL8570424 | 0.92 | CNR2 (0.40) | CNR2CNR1FAAHPTPN11MEN1 | |
| SCHEMBL8568941 | 0.91 | CNR2 (0.39) | CNR2CNR1FAAHPTPN11LMNA | |
| SCHEMBL8570566 | 0.90 | CNR1 (0.38) | CNR2CNR1FAAHLMNA | |
| SCHEMBL8569983 | 0.90 | CNR2 (0.38) | CNR2CNR1FAAHPPARGPPARD | |
| SCHEMBL8570958 | 0.89 | HIF1A (0.38) | CNR2CNR1FAAHMEN1LMNA | |
| SCHEMBL8574818 | 0.89 | HIF1A (0.37) | CNR2CNR1FAAHCYP2C9LMNA | |
| SCHEMBL8570623 | 0.87 | RAB9A (0.38) | CNR2CNR1FAAHPPARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | claimed |
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |