Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 2/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566872 | 0.92 | CNR2 (0.47) | CNR2FAAHCNR1LMNAPTPN11 | |
| SCHEMBL8569219 | 0.92 | CNR2 (0.47) | CNR2FAAHCNR1LMNAPTPN11 | |
| SCHEMBL8567786 | 0.92 | CNR2 (0.47) | CNR2FAAHCNR1LMNAPTPN11 | |
| SCHEMBL8572650 | 0.92 | CNR2 (0.47) | CNR2FAAHCNR1LMNAPTPN11 | |
| SCHEMBL8568941 | 0.91 | CNR2 (0.39) | CNR2FAAHCNR1RARAHIF1A | |
| SCHEMBL8570566 | 0.90 | CNR1 (0.38) | CNR2FAAHCNR1HIF1AEPAS1 | |
| SCHEMBL8569983 | 0.90 | CNR2 (0.38) | CNR2FAAHCNR1HIF1AEPAS1 | |
| SCHEMBL8570958 | 0.89 | HIF1A (0.38) | CNR2FAAHCNR1RARAHIF1A | |
| SCHEMBL8574818 | 0.89 | HIF1A (0.37) | CNR2FAAHCNR1IKBKBRARA | |
| SCHEMBL8570623 | 0.87 | RAB9A (0.38) | CNR2FAAHCNR1HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | claimed |
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |