Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 5/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568941 | 0.96 | CNR2 (0.39) | HIF1AEPAS1CNR2CNR1KDM4E | |
| SCHEMBL8570623 | 0.90 | RAB9A (0.38) | HIF1AEPAS1CNR2CNR1KDM4E | |
| SCHEMBL8567786 | 0.89 | CNR2 (0.47) | CNR2CNR1FAAHALDH1A1LMNA | |
| SCHEMBL8566872 | 0.89 | CNR2 (0.47) | CNR2CNR1FAAHALDH1A1LMNA | |
| SCHEMBL8574818 | 0.89 | HIF1A (0.37) | HIF1AEPAS1CNR2CNR1KDM4E | |
| SCHEMBL8569219 | 0.89 | CNR2 (0.47) | CNR2CNR1FAAHALDH1A1LMNA | |
| SCHEMBL8572650 | 0.89 | CNR2 (0.47) | CNR2CNR1FAAHALDH1A1LMNA | |
| SCHEMBL8570424 | 0.89 | CNR2 (0.40) | HIF1AEPAS1CNR2CNR1KDM4E | |
| SCHEMBL8570566 | 0.89 | CNR1 (0.38) | HIF1AEPAS1CNR2CNR1KDM4E | |
| SCHEMBL8569983 | 0.88 | CNR2 (0.38) | HIF1AEPAS1CNR2CNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | claimed |
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |