Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 7/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.34 |
| ▸ | HPGDS | O60760 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28590572 | 0.71 | HPGDS (0.49) | PTPN2PTPN1LDHABAZ2BCYP11B1 | |
| SCHEMBL28599514 | 0.71 | HPGDS (0.49) | PTPN2PTPN1LDHABAZ2BCYP11B1 | |
| SCHEMBL9057614 | 0.69 | BAZ2B (0.53) | PTPN2PTPN1LDHABAZ2BWNT3A | |
| SCHEMBL22589209 | 0.69 | ALDH1A1 (0.52) | PTPN2PTPN1LDHABAZ2BWNT3A | |
| SCHEMBL27676919 | 0.69 | PTPN2 (0.50) | PTPN2PTPN1LDHABAZ2BWNT3A | |
| Hydrochloric Acid SCHEMBL23235071 | 0.67 | PTPN2 (0.49) | PTPN2PTPN1LDHABAZ2BWNT3A | |
| SCHEMBL4870704 | 0.65 | PTPN1 (0.67) | PTPN2PTPN1LDHABAZ2BWNT3A | |
| SCHEMBL27405407 | 0.65 | TDP1 (0.50) | PTPN2PTPN1LDHABAZ2BWNT3A | |
| SCHEMBL8562167 | 0.65 | GAA (0.45) | — | |
| SCHEMBL28697805 | 0.64 | HDAC4 (0.54) | PTPN2PTPN1WNT3ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814646-A | TREATING THE PROGRESSION OF ALZHEIMER'S DISEASE, BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 1998-09-29 | — | — | US | disclosed |