Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32669360 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTPOLBESR2 | |
| SCHEMBL32669436 | 0.84 | ALDH1A1 (0.43) | ALDH1A1MAPTHTTPOLBESR2 | |
| SCHEMBL8564029 | 0.84 | KDM4E (0.55) | ALDH1A1MAPTHTTPOLBESR2 | |
| SCHEMBL11617288 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPTHTTPOLBESR2 | |
| SCHEMBL8560948 | 0.82 | MAPT (0.51) | ALDH1A1MAPTHTTPOLBESR2 | |
| SCHEMBL17674239 | 0.81 | KMT2A (0.56) | ALDH1A1MAPTHTTPOLBESR2 | |
| SCHEMBL17673916 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTHTTPOLBESR2 | |
| SCHEMBL17674161 | 0.78 | L3MBTL1 (0.54) | ALDH1A1MAPTHTTPOLBESR2 | |
| SCHEMBL20066139 | 0.77 | KMT2A (0.46) | ALDH1A1MAPTHTTPOLBESR2 | |
| SCHEMBL8563829 | 0.76 | MAPK1 (0.37) | ALDH1A1MAPTHTTPOLBESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |