Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560442 | 0.85 | KDM4E (0.45) | ALDH1A1POLBMAPTRAB9AKDM4E | |
| SCHEMBL8567497 | 0.85 | ALDH1A1 (0.42) | ALDH1A1HTTPOLBMAPTESR2 | |
| SCHEMBL8597579 | 0.77 | HTT (0.40) | ALDH1A1HTTPOLBMAPTESR2 | |
| SCHEMBL8561844 | 0.77 | MAPT (0.41) | MAPK1ALDH1A1HTTMAPTNPC1 | |
| SCHEMBL8567678 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HTTPOLBMAPTESR2 | |
| SCHEMBL32669360 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HTTPOLBMAPTESR2 | |
| SCHEMBL3709618 | 0.75 | GAA (0.39) | MAPK1ALDH1A1HTTPOLBMAPT | |
| SCHEMBL3218043 | 0.75 | NOS3 (0.50) | ALDH1A1HTTPOLBMAPTESR2 | |
| SCHEMBL8563396 | 0.75 | CES2 (0.39) | ALDH1A1HTTPOLBMAPTESR2 | |
| SCHEMBL30898769 | 0.74 | NOS3 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |