Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 5/20 | 0.47 |
| ▸ | RARB | P10826 | 5/20 | 0.47 |
| ▸ | RARG | P13631 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567722 | 0.85 | RARA (0.51) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL6378001 | 0.82 | RARA (0.65) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8567955 | 0.81 | FAAH (0.47) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8566037 | 0.80 | FAAH (0.42) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8570953 | 0.80 | RARA (0.39) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8569797 | 0.80 | RARA (0.46) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8568931 | 0.79 | RARA (0.40) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8570613 | 0.79 | RARA (0.38) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8574331 | 0.78 | RARB (0.36) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8566864 | 0.78 | CNR2 (0.47) | RARARARBRARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | claimed |
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |