Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.59 |
| ▸ | RXRA | P19793 | 5/20 | 0.59 |
| ▸ | RARA | P10276 | 4/20 | 0.59 |
| ▸ | RARB | P10826 | 4/20 | 0.59 |
| ▸ | RARG | P13631 | 4/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | BLM | P54132 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | RXRB | P28702 | 2/20 | 0.59 |
| ▸ | RXRG | P48443 | 2/20 | 0.59 |
| ▸ | RORC | P51449 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | HTR2B | P41595 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isotretinoin Anisatil SCHEMBL14161050 | 1.00 | RBP4 (0.59) | RBP4ALDH1A1MAPTCYP3A4RXRA | |
| Isotretinoin Anisatil SCHEMBL4904949 | 1.00 | RBP4 (0.59) | RBP4ALDH1A1MAPTCYP3A4RXRA | |
| Isotretinoin Anisatil SCHEMBL8597493 | 1.00 | RBP4 (0.59) | RBP4ALDH1A1MAPTCYP3A4RXRA | |
| Isotretinoin Anisatil SCHEMBL4784232 | 1.00 | RBP4 (0.59) | RBP4ALDH1A1MAPTCYP3A4RXRA | |
| SCHEMBL8984781 | 0.93 | ALDH1A1 (0.59) | RBP4ALDH1A1MAPTCYP3A4RXRA | |
| SCHEMBL8984722 | 0.92 | ALDH1A1 (0.64) | RBP4ALDH1A1MAPTCYP3A4RXRA | |
| SCHEMBL8984755 | 0.92 | RBP4 (0.61) | RBP4ALDH1A1MAPTCYP3A4RXRA | |
| SCHEMBL8984824 | 0.91 | ALDH1A1 (0.65) | RBP4ALDH1A1MAPTCYP3A4RXRA | |
| SCHEMBL8984703 | 0.90 | ALDH1A1 (0.60) | RBP4ALDH1A1MAPTCYP3A4RXRA | |
| SCHEMBL342372 | 0.90 | ALDH1A1 (0.65) | RBP4ALDH1A1MAPTCYP3A4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837728-A | ACNE AND OTHER SKIN DISORDERS; ANTIAGING, ANTIWRINKLING AND WOUND HEALING AGENTS; SIDE EFFECT REDUCTION | MOLECULAR DESIGN INTERNATIONAL (US) | 1998-11-17 | — | — | US | disclosed |
| WO-1997032839-A9 | 9-CIS-RETINOIC ACID ESTERS AND AMIDES AND USES THEREOF | — | 1998-07-16 | — | — | WO | disclosed |