Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481279 | 0.84 | TDP1 (0.47) | TDP1TSHRALDH1A1MAPTMEN1 | |
| SCHEMBL15804255 | 0.81 | CYP3A4 (0.39) | TDP1TSHRALDH1A1MAPTMEN1 | |
| SCHEMBL30563095 | 0.76 | HSD17B10 (0.50) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL1815079 | 0.76 | TDP1 (0.47) | TDP1TSHRALDH1A1MAPTMEN1 | |
| SCHEMBL3059949 | 0.76 | TSHR (0.47) | TDP1TSHRPDE7AMAPK1HSD17B10 | |
| SCHEMBL741363 | 0.76 | ALDH1A1 (0.36) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10547254 | 0.76 | GPR35 (0.46) | TDP1TSHRALDH1A1MAPTMEN1 | |
| SCHEMBL172188 | 0.76 | HSD17B10 (0.50) | TDP1TSHRALDH1A1MAPTCYP3A4 | |
| SCHEMBL20924322 | 0.74 | ALDH1A1 (0.44) | TDP1TSHRALDH1A1MAPTMEN1 | |
| SCHEMBL3341806 | 0.73 | ALDH1A1 (0.40) | TDP1TSHRALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014140592-A1 | IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS | PROXIMAGEN LIMITED (GB) | 2014-09-18 | — | — | WO | disclosed |
| CN-1089757-C | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 2002-08-28 | — | — | CN | disclosed |
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| CN-1138033-A | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |
| EP-0095278-B1 | 5-OXO-2-PYRROLIDINEPROPANOIC ACID DERIVATIVES AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-11-30 | — | — | EP | disclosed |
| US-4617310-A | 5-oxo-2-pyrrolidinepropanoic acid derivatives and use as cognition activators | WARNER-LAMBERT COMPANY (US) | 1986-10-14 | — | — | US | disclosed |
| US-4559358-A | TREATING SENILITY | WARNER-LAMBERT COMPANY (US) | 1985-12-17 | — | — | US | disclosed |
| EP-0095278-A2 | 5-Oxo-2-pyrrolidinepropanoic acid derivatives and their production | WARNER-LAMBERT COMPANY (US) | 1983-11-30 | — | — | EP | disclosed |