Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15804255 | 0.78 | CYP3A4 (0.39) | ALDH1A1HPGDTSHRPOLBTDP1 | |
| SCHEMBL4726250 | 0.78 | MAPT (0.43) | ALDH1A1HPGDPOLBHTTTDP1 | |
| SCHEMBL172188 | 0.77 | HSD17B10 (0.50) | ALDH1A1HPGDTSHRHTTTDP1 | |
| SCHEMBL30563095 | 0.77 | HSD17B10 (0.50) | ALDH1A1HPGDTSHRHTTTDP1 | |
| SCHEMBL3057719 | 0.76 | LMNA (0.50) | ALDH1A1POLBHTTLMNAMAPT | |
| SCHEMBL3888217 | 0.75 | HTT (0.51) | ALDH1A1HPGDTSHRPOLBHTT | |
| SCHEMBL21067091 | 0.74 | NPC1 (0.46) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL10547254 | 0.73 | GPR35 (0.46) | ALDH1A1HPGDTSHRTDP1SNCA | |
| SCHEMBL741363 | 0.73 | ALDH1A1 (0.36) | ALDH1A1HTTTDP1MEN1KMT2A | |
| SCHEMBL8568031 | 0.73 | TDP1 (0.47) | ALDH1A1TSHRPOLBTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |