Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CLPP | Q16740 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563163 | 0.89 | MEN1 (0.48) | PDE3BPDE3AKMT2AMEN1LMNA | |
| SCHEMBL16264683 | 0.75 | SLC6A5 (0.49) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL9256480 | 0.75 | HPGD (0.51) | KMT2AMEN1ALDH1A1L3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL4793706 | 0.74 | HPGD (0.50) | KMT2AMEN1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL31376614 | 0.73 | MEN1 (0.50) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL2078909 | 0.73 | MAPT (0.54) | KMT2AMEN1LMNAGLAALDH1A1 | |
| SCHEMBL8561824 | 0.72 | SLC6A5 (0.47) | KMT2AMEN1CLPPALDH1A1MAPT | |
| SCHEMBL8567999 | 0.71 | SLC6A5 (0.43) | KMT2AMEN1LMNAL3MBTL1TNF | |
| SCHEMBL8566446 | 0.70 | SLC6A5 (0.42) | KMT2AMEN1LMNAMAPTTNF | |
| SCHEMBL977652 | 0.70 | MEN1 (0.52) | KMT2AMEN1LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588500-B1 | 3-Oxadiazolyl-1,6-naphthyridine derivatives with affinity for benzodiazepine receptors | DAINIPPON PHARMACEUTICAL CO (JP) | 1998-11-04 | — | — | EP | disclosed |
| US-5424433-A | Benzodiazepine receptor agonist | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| US-5424434-A | Intramolecular cyclodehydration with a phosphorus(III) compound and a dialkyl azodicarboxylate in presence of a base to form a benzodiazepine receptor agonist, anxiolytic agent | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| US-5367078-A | Benzodiazine receptor agonists | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1994-11-22 | — | — | US | disclosed |
| EP-0588500-A2 | 3-Oxadiazolyl-1,6-naphthyridine derivatives with affinity for benzodiazepine receptors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |