Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1755131 | 1.00 | PKM (0.55) | PKMALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL2914715 | 0.94 | PKM (0.56) | PKMALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL4650366 | 0.89 | PKM (0.70) | PKMALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL4649818 | 0.89 | PKM (0.59) | PKMALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL8113725 | 0.89 | PKM (0.59) | PKMALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL4649757 | 0.89 | PKM (0.59) | PKMALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL1888725 | 0.88 | ALDH1A1 (0.51) | PKMALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL2911879 | 0.85 | PKM (0.47) | PKMALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL2905614 | 0.84 | GAA (0.56) | PKMALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL9646422 | 0.84 | PKM (0.69) | PKMALDH1A1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834601-A | DYEING CELLULOSE, WOOL, POLYAMIDE | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 1998-11-10 | — | — | US | disclosed |