Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MGMT | P16455 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116983 | 0.80 | KMT2A (0.50) | CYP19A1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL1699178 | 0.79 | CYP19A1 (0.42) | CYP19A1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL8568481 | 0.79 | HTT (0.50) | CYP19A1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL8565247 | 0.78 | ALDH1A1 (0.41) | MEN1KMT2AMAPTHTTKDM4E | |
| SCHEMBL8563396 | 0.77 | CES2 (0.39) | MEN1KMT2AMAPTHTTKDM4E | |
| SCHEMBL8566190 | 0.77 | KMT2A (0.58) | CYP19A1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL8565267 | 0.75 | MEN1 (0.50) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8562887 | 0.75 | BACE1 (0.52) | MEN1KMT2AMAPTHTTKDM4E | |
| SCHEMBL7499087 | 0.75 | LTA4H (0.43) | — | |
| SCHEMBL8568534 | 0.75 | CYP19A1 (0.40) | CYP19A1CYP11B1CYP11B2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |