Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564866 | 0.82 | EGFR (0.41) | EGFRALDH1A1TDP1MAPTLMNA | |
| SCHEMBL5252473 | 0.80 | TDP1 (0.48) | EGFRALDH1A1TDP1MAPTLMNA | |
| SCHEMBL24455815 | 0.78 | NOS3 (0.50) | EGFRALDH1A1TDP1MAPTLMNA | |
| SCHEMBL29563051 | 0.77 | ALDH1A1 (0.49) | EGFRALDH1A1TDP1MAPTLMNA | |
| SCHEMBL22498154 | 0.77 | ALDH1A1 (0.47) | EGFRALDH1A1TDP1MAPTLMNA | |
| SCHEMBL28115052 | 0.77 | TDP1 (0.46) | EGFRALDH1A1TDP1MAPTLMNA | |
| SCHEMBL8564092 | 0.77 | MAPK1 (0.47) | EGFRALDH1A1TDP1MAPTCYP3A4 | |
| SCHEMBL474593 | 0.77 | NOS3 (0.52) | ALDH1A1TDP1MAPTLMNAHTT | |
| SCHEMBL29492839 | 0.77 | NOS3 (0.52) | ALDH1A1TDP1MAPTLMNAHTT | |
| SCHEMBL57031 | 0.77 | ALDH1A1 (0.49) | EGFRALDH1A1TDP1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |