Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.52 |
| ▸ | NOS1 | P29475 | 2/20 | 0.52 |
| ▸ | NOS2 | P35228 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29492839 | 1.00 | NOS3 (0.52) | NOS3NOS1NOS2ALDH1A1MAPT | |
| SCHEMBL4888907 | 0.85 | NOS3 (0.52) | NOS3NOS1NOS2ALDH1A1MAPT | |
| SCHEMBL3085354 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8564866 | 0.82 | EGFR (0.41) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30197179 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL843761 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5252473 | 0.80 | TDP1 (0.48) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL24455815 | 0.78 | NOS3 (0.50) | NOS3NOS1NOS2ALDH1A1MAPT | |
| SCHEMBL8564092 | 0.77 | MAPK1 (0.47) | ALDH1A1MAPTCYP1A2CYP2C9TSHR | |
| SCHEMBL22498154 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTTSHRCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250231190-A1 | ENHANCED FLUORESCENCE SIGNAL THROUGH THE APPLICATION OF AROMATIC ADDITIVES ONTO THE MICROSCOPY SAMPLE FOR STANDARD FLUORESCENCE, FLUORESCENCE MICROSCOPY AND COMBINED FLUORESCENCE MALDI MICROSCOPY/IMAGING | THE JOHNS HOPKINS UNIVERSITY | 2025-07-17 | — | — | US | claimed |
| US-20240096612-A1 | METHOD FOR MASS SPECTROMETRY OF ORGANIC SYNTHETIC COMPOUND | SHIMADZU CORPORATION (JP) | 2024-03-21 | — | — | US | claimed |
| EP-4293350-A1 | METHOD FOR MASS SPECTROMETRY OF ORGANIC SYNTHETIC COMPOUND | Shimadzu Corporation (JP) | 2023-12-20 | — | — | EP | claimed |
| WO-2023205280-A1 | ENHANCED FLUORESCENCE SIGNAL THROUGH THE APPLICATION OF AROMATIC ADDITIVES ONTO THE MICROSCOPY SAMPLE FOR STANDARD FLUORESCENCE, FLUORESCENCE MICROSCOPY AND COMBINED FLUORESCENCE MALDI MICROSCOPY/IMAGING | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-10-26 | — | — | WO | claimed |
| WO-2023205279-A1 | IMPROVED RAMAN SPECTROSCOPY WITH THE ADDITION OF AROMATIC COMPOUNDS | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-10-26 | — | — | WO | claimed |
| CN-116917726-A | Mass spectrometry of organic synthetic compounds | 株式会社岛津制作所 | 2023-10-20 | — | — | CN | claimed |
| WO-2022172500-A1 | METHOD FOR MASS SPECTROMETRY OF ORGANIC SYNTHETIC COMPOUND | 株式会社 島津製作所 | 2022-08-18 | — | — | WO | claimed |
| EP-3183553-B1 | METHOD OF SAMPLE PREPARATION FOR MALDI AND AUTOMATED SYSTEM THEREFOR | BECTON DICKINSON CO (US) | 2022-01-12 | — | — | EP | claimed |
| CN-107076651-B | Sample preparation method for MALDI and automated system therefor | 贝克顿·迪金森公司 | 2021-04-06 | — | — | CN | claimed |
| EP-3341111-B1 | COATING OF AEROSOL PARTICLES USING AN ACOUSTIC COATER | ZETEO TECH INC (US) | 2020-09-30 | — | — | EP | claimed |
| EP-3183553-A1 | METHOD OF SAMPLE PREPARATION FOR MALDI AND AUTOMATED SYSTEM THEREFOR | Becton, Dickinson and Company (US) | 2017-06-28 | — | — | EP | claimed |
| WO-2016028684-A1 | METHOD OF SAMPLE PREPARATION FOR MALDI AND AUTOMATED SYSTEM THEREFOR | BECTON, DICKINSON AND COMPANY (US) | 2016-02-25 | — | — | WO | claimed |
| US-9012838-B2 | Covalently functionalized nanodiamond-based MALDI matrices and methods of use thereof | UNIVERSITY OF SASKATCHEWAN (CA) | 2015-04-21 | — | — | US | claimed |
| US-20140312218-A1 | COVALENTLY FUNCTIONALIZED NANODIAMOND-BASED MALDI MATRICES AND METHODS OF USE THEREOF | UNIVERSITY OF SASKATCHEWAN (CA) | 2014-10-23 | — | — | US | claimed |
| US-7547713-B2 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2009-06-16 | — | — | US | claimed |
| CN-1284773-C | Ortho-pyridinequinone derivative, composite containing said derivative, its preparation method and application | BAIRUI GLOBAL CO LTD (VG) | 2006-11-15 | — | — | CN | claimed |
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | GU LIANQUAN | 2006-05-25 | — | — | US | claimed |
| CN-1477099-A | O-pyridinoquinone derivative, composition containing the same, preparation method and use of the same | 百瑞全球有限公司 | 2004-02-25 | — | — | CN | claimed |
| CN-1139606-C | Norbornene catalytic system and its preparation method and application | 中国科学院化学研究所 | 2004-02-25 | — | — | CN | claimed |
| CN-1394685-A | Norbornene catalytic system and its preparation method and application | CHINESE ACAD INST CHEMISTRY (CN) | 2003-02-05 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111405-A1 | O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives | PTGS2, PTGES2, PTGES | NOS3 224/4885NOS1 252/4885NOS2 113/4885 |
| US-20140312218-A1 | COVALENTLY FUNCTIONALIZED NANODIAMOND-BASED MALDI MATRICES AND METHODS OF USE THEREOF | ITGA2B, MMP2, ITGAV | NOS3 911/4885NOS1 1411/4885NOS2 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.