SCHEMBL8568661

SCHEMBL8568661

O=C(CI)OP(=O)(O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9724295 0.80 FDPS (0.39)
SCHEMBL8568659 0.80 KDM4E (0.33)
SCHEMBL10563126 0.77 CA4 (0.48)
SCHEMBL285627 0.77 CA4 (0.48)
SCHEMBL28118806 0.76 CA1 (0.46)
SCHEMBL368535 0.74
SCHEMBL9619452 0.74 CA4 (0.46)
SCHEMBL1643232 0.74 CA4 (0.46)
SCHEMBL27473070 0.74 CA4 (0.46)
SCHEMBL10625772 0.72 BLM (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1342156-A Inhibition and treatment of hepatitis B virus and flavivirus by helioxanthin and its analogs UNIV YALE (US) 2002-03-27 CN disclosed
US-5834183-A FOR DIAGNOSIS OF AUTOSOMAL DOMINANT SPINOCEREBELLAR ATAXIA TYPE 1 GENE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1998-11-10 US disclosed
EP-0707647-A1 GENE SEQUENCE FOR SPINOCEREBELLAR ATAXIA TYPE 1 AND METHOD FOR DIAGNOSIS THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1996-04-24 EP disclosed
WO-1995001437-A2 GENE SEQUENCE FOR SPINOCEREBELLAR ATAXIA TYPE 1 AND METHOD FOR DIAGNOSIS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1995-01-12 WO disclosed