Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BTN3A1 | O00481 | 3/20 | 0.35 |
| ▸ | MVD | P53602 | 4/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568661 | 0.80 | — | — | |
| SCHEMBL27598095 | 0.79 | BTN3A1 (0.41) | FDPSBLMTDP1BTN3A1MVD | |
| SCHEMBL28622490 | 0.77 | BTN3A1 (0.39) | FDPSBLMTDP1BTN3A1MVD | |
| SCHEMBL28212721 | 0.76 | BTN3A1 (0.38) | FDPSBLMTDP1BTN3A1MVD | |
| SCHEMBL13517005 | 0.76 | FDPS (0.38) | FDPSBLMTDP1BTN3A1MVD | |
| SCHEMBL30098820 | 0.74 | ALDH1A1 (0.44) | FDPSBLMTDP1BTN3A1MVD | |
| SCHEMBL27498478 | 0.74 | BTN3A1 (0.36) | FDPSBLMTDP1BTN3A1MVD | |
| SCHEMBL4957043 | 0.74 | MVD (0.41) | FDPSBLMTDP1BTN3A1MVD | |
| SCHEMBL27725614 | 0.72 | PEPD (0.39) | FDPSBLMTDP1BTN3A1MVD | |
| SCHEMBL8568659 | 0.72 | KDM4E (0.33) | BLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5165927-A | Cysteine modified to reduce ADP-ribosyl transferase activity | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1992-11-24 | — | — | US | disclosed |
| US-5032398-A | Polyphosphate, sulfhydryl reductant, detergent | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1991-07-16 | — | — | US | disclosed |