Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568661 | 0.80 | — | — | |
| SCHEMBL28118806 | 0.78 | CA1 (0.46) | KDM4EGMNNUSP2ALDH1A1LMNA | |
| SCHEMBL9724295 | 0.72 | FDPS (0.39) | BLMTDP1 | |
| SCHEMBL939429 | 0.71 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL18614747 | 0.69 | — | — | |
| SCHEMBL56558 | 0.67 | — | — | |
| SCHEMBL23827519 | 0.67 | LDHA (0.40) | LMNAHPGDBLMTDP1 | |
| SCHEMBL17606428 | 0.65 | MMP1 (0.43) | ALDH1A1ALOX15TDP1 | |
| SCHEMBL4598746 | 0.65 | ALDH1A1 (0.52) | ALDH1A1LMNACYP3A4 | |
| SCHEMBL16215470 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834183-A | FOR DIAGNOSIS OF AUTOSOMAL DOMINANT SPINOCEREBELLAR ATAXIA TYPE 1 GENE | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1998-11-10 | — | — | US | disclosed |
| EP-0707647-A1 | GENE SEQUENCE FOR SPINOCEREBELLAR ATAXIA TYPE 1 AND METHOD FOR DIAGNOSIS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001437-A2 | GENE SEQUENCE FOR SPINOCEREBELLAR ATAXIA TYPE 1 AND METHOD FOR DIAGNOSIS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1995-01-12 | — | — | WO | disclosed |