Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.50 |
| ▸ | RRM1 | P23921 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901234 | 0.94 | DPP7 (0.53) | DPP7RRM1ALDH1A1DPP8DPP9 | |
| SCHEMBL19547625 | 0.91 | NOD1 (0.47) | DPP7RRM1ALDH1A1DPP8DPP9 | |
| SCHEMBL855574 | 0.91 | NOD1 (0.47) | DPP7RRM1ALDH1A1DPP8DPP9 | |
| SCHEMBL856465 | 0.89 | GNAI3 (0.51) | DPP7RRM1ALDH1A1DPP8DPP9 | |
| SCHEMBL2494020 | 0.89 | GNAI3 (0.51) | DPP7RRM1ALDH1A1DPP8DPP9 | |
| SCHEMBL16330780 | 0.89 | ALDH1A1 (0.47) | DPP7RRM1ALDH1A1NOD1ATM | |
| SCHEMBL16330782 | 0.89 | ALDH1A1 (0.47) | DPP7RRM1ALDH1A1NOD1ATM | |
| SCHEMBL1097461 | 0.88 | NOD1 (0.50) | DPP7ALDH1A1DPP8DPP9NOD1 | |
| SCHEMBL4957809 | 0.88 | NOD1 (0.50) | DPP7ALDH1A1DPP8DPP9NOD1 | |
| SCHEMBL16710358 | 0.88 | ALDH1A1 (0.50) | DPP7ALDH1A1DPP8DPP9NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432760-A1 | BRIDGED SPIRO [2.4]HEPTANE DERIVATIVES AS ALX RECEPTOR AND/OR FPRL2 AGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010134014-A1 | BRIDGED SPIRO [2.4] HEPTANE DERIVATIVES AS ALX RECEPTOR AND/OR FPRL2 AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-11-25 | — | — | WO | disclosed |
| EP-1349956-A2 | REPLICABLE PROBE ARRAY | SurModics, Inc. (US) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002010450-A2 | REPLICABLE PROBE ARRAY | SURMODICS, INC. (US) | 2002-02-07 | — | — | WO | disclosed |
| WO-2002000614-A1 | ARYL COMPOUNDS, THEIR PREPARATION AND THEIR USE IN THERAPY | RIBOTARGETS LIMITED (GB) | 2002-01-03 | — | — | WO | disclosed |