Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31475345 | 0.80 | MAPT (0.47) | MAPTALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL8562235 | 0.80 | TDP1 (0.48) | MAPTALDH1A1CYP3A4ALOX15HPGD | |
| SCHEMBL8568828 | 0.80 | TDP1 (0.48) | MAPTALDH1A1CYP3A4ALOX15HPGD | |
| SCHEMBL8566803 | 0.78 | ALOX15 (0.44) | MAPTALDH1A1CYP3A4ALOX15HPGD | |
| SCHEMBL8566378 | 0.77 | ALDH1A1 (0.36) | MAPTALDH1A1CYP3A4ALOX15HPGD | |
| SCHEMBL3770753 | 0.77 | MAPT (0.45) | MAPTALDH1A1CYP3A4TDP1LMNA | |
| SCHEMBL31289923 | 0.77 | MAPT (0.45) | MAPTALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL8567243 | 0.77 | CA2 (0.38) | MAPTALDH1A1ALOX15HPGDNPY1R | |
| SCHEMBL899057 | 0.73 | MAPT (0.41) | MAPTALDH1A1CYP3A4ALOX15HPGD | |
| SCHEMBL8569645 | 0.73 | ALDH1A1 (0.42) | MAPTALDH1A1CYP3A4ALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658646-A | Aminoheteroaryl benzamides as kinase inhibitors | 诺华股份有限公司 | 2016-06-08 | — | — | CN | disclosed |