Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953590 | 0.70 | CYP11B2 (0.44) | CYP11B2KDM4EHSD17B10HTTTSHR | |
| SCHEMBL7590017 | 0.70 | CYP11B2 (0.44) | CYP11B2KDM4EHSD17B10HTTTSHR | |
| SCHEMBL7590158 | 0.65 | CYP11B2 (0.56) | CYP11B2KDM4EHSD17B10HTTTSHR | |
| SCHEMBL7967494 | 0.64 | CYP11B2 (0.41) | CYP11B2KDM4EHSD17B10HTTTSHR | |
| SCHEMBL7961492 | 0.64 | CYP11B2 (0.43) | CYP11B2KDM4EHSD17B10HTTTSHR | |
| SCHEMBL5744189 | 0.62 | DYRK1A (0.57) | CYP11B2KDM4EHSD17B10HTTTSHR | |
| SCHEMBL3162665 | 0.61 | NTRK1 (0.54) | CYP11B2KDM4EHSD17B10HTTDYRK1A | |
| Hydrochloric Acid SCHEMBL5743585 | 0.61 | DYRK1A (0.56) | CYP11B2KDM4EHSD17B10HTTTSHR | |
| SCHEMBL7587234 | 0.60 | ABCC1 (0.44) | CYP11B2KDM4EHSD17B10HTTTSHR | |
| SCHEMBL23973953 | 0.60 | CYP11B2 (0.47) | CYP11B2KDM4EHSD17B10HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833635-A1 | NOVEL USE FOR PYRROLE DERIVATIVES | Aventis Pharma S.A. (FR) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000073-A1 | NOVEL USE FOR PYRROLE DERIVATIVES | RHONE-POULENC RORER S.A. (FR) | 1997-01-03 | — | — | WO | disclosed |