Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.46 |
| ▸ | RARA | P10276 | 4/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | GOT1 | P17174 | 1/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571683 | 0.95 | IKBKB (0.48) | IKBKBRARAS1PR1RARGLMNA | |
| SCHEMBL8570403 | 0.83 | LMNA (0.41) | RARAS1PR1RARGLMNATDP1 | |
| SCHEMBL8572145 | 0.82 | RARA (0.55) | IKBKBRARAS1PR1RARGLMNA | |
| SCHEMBL8397932 | 0.82 | IKBKB (0.48) | IKBKBRARAS1PR1RARGLMNA | |
| SCHEMBL8568927 | 0.81 | S1PR1 (0.34) | IKBKBRARAS1PR1RARGLMNA | |
| SCHEMBL8572262 | 0.80 | IKBKB (0.51) | IKBKBRARAS1PR1RARGLMNA | |
| SCHEMBL8617074 | 0.80 | RARA (0.60) | IKBKBRARAS1PR1RARGLMNA | |
| SCHEMBL8428797 | 0.80 | RARA (0.47) | IKBKBRARAS1PR1RARGLMNA | |
| SCHEMBL9090600 | 0.79 | IKBKB (0.51) | IKBKBRARAS1PR1RARGLMNA | |
| SCHEMBL8566497 | 0.78 | RARA (0.50) | IKBKBRARAS1PR1RARGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |
| EP-0679631-B1 | Biaromatic acetylated, an adamantyl group containing compounds, pharmaceutical and cosmetic compositions containing them and their use | CIRD GALDERMA (FR) | 1998-05-06 | — | — | EP | disclosed |
| US-5574036-A | Adamantyl-substituted polycyclic acetylene compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1996-11-12 | — | — | US | disclosed |
| EP-0679631-A1 | Biaromatic acetylated, an adamantyl group containing compounds, pharmaceutical and cosmetic compositions containing them and their use | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1995-11-02 | — | — | EP | disclosed |