Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 8/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574975 | 0.84 | CNR2 (0.39) | MAPK1LMNAL3MBTL1ADORA3CNR2 | |
| SCHEMBL8570897 | 0.79 | CNR2 (0.40) | MAPK1LMNAL3MBTL1ADORA3CNR2 | |
| SCHEMBL8570978 | 0.76 | MEN1 (0.37) | MAPK1LMNAL3MBTL1CNR2NPC1 | |
| SCHEMBL8573237 | 0.74 | CNR2 (0.33) | MAPK1LMNAL3MBTL1CNR2NPC1 | |
| SCHEMBL8575210 | 0.74 | CNR2 (0.32) | MAPK1LMNAL3MBTL1ADORA3CNR2 | |
| SCHEMBL8570612 | 0.71 | PDE4D (0.30) | — | |
| SCHEMBL8571821 | 0.71 | — | — | |
| SCHEMBL8616809 | 0.70 | RARA (0.41) | LMNACNR2HIF1AEPAS1EPHX2 | |
| SCHEMBL8658216 | 0.68 | HDAC11 (0.35) | LMNACNR2HIF1AMEN1KMT2A | |
| SCHEMBL8569800 | 0.68 | FFAR1 (0.35) | MAPK1LMNAL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |