Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570897 | 0.88 | CNR2 (0.40) | NPC1RAB9AMAPK1LMNAKDM4E | |
| SCHEMBL8570978 | 0.84 | MEN1 (0.37) | NPC1RAB9AMAPK1LMNAEPHX2 | |
| SCHEMBL8574975 | 0.75 | CNR2 (0.39) | NPC1RAB9AMAPK1LMNAKDM4E | |
| SCHEMBL8567757 | 0.72 | HNF4A (0.46) | FFAR1NPC1RAB9AMAPK1P2RX7 | |
| SCHEMBL8569804 | 0.70 | EPHX2 (0.35) | NPC1MAPK1P2RX7KDM4EEPHX2 | |
| SCHEMBL6770716 | 0.70 | APP (0.41) | FFAR1NPC1RAB9AP2RX7LMNA | |
| SCHEMBL8571816 | 0.67 | EPHX2 (0.40) | P2RX7LMNAEPHX2KMT2ASMN1; SMN2 | |
| SCHEMBL6684731 | 0.66 | LMNA (0.53) | FFAR1NPC1RAB9ALMNAEPHX2 | |
| SCHEMBL8567726 | 0.66 | CNR2 (0.41) | P2RX7LMNAKDM4EEPHX2MEN1 | |
| SCHEMBL8570979 | 0.65 | EPHX2 (0.40) | P2RX7LMNAEPHX2KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | claimed |
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |