Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574975 | 0.88 | CNR2 (0.39) | CNR2LMNAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8569800 | 0.88 | FFAR1 (0.35) | LMNAL3MBTL1KDM4EMAPK1NPC1 | |
| SCHEMBL8569003 | 0.79 | MAPK1 (0.35) | CNR2LMNAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8570978 | 0.79 | MEN1 (0.37) | CNR2LMNAL3MBTL1MAPK1NPC1 | |
| SCHEMBL8573061 | 0.68 | KDM4E (0.41) | CNR2LMNAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8571816 | 0.67 | EPHX2 (0.40) | CNR2LMNAALDH1A1HIF1AEPAS1 | |
| SCHEMBL8567726 | 0.67 | CNR2 (0.41) | CNR2LMNAKDM4EHIF1AEPAS1 | |
| SCHEMBL6770716 | 0.66 | APP (0.41) | LMNAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL8567757 | 0.65 | HNF4A (0.46) | LMNAKDM4EALDH1A1MAPK1NPC1 | |
| SCHEMBL8572203 | 0.65 | CNR2 (0.35) | CNR2LMNAL3MBTL1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |