Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569048 | 1.00 | KMT2A (0.45) | KMT2AMEN1POLBMAPK1TDP2 | |
| SCHEMBL8569043 | 1.00 | KMT2A (0.45) | KMT2AMEN1POLBMAPK1TDP2 | |
| SCHEMBL10148374 | 0.87 | ALDH1A1 (0.42) | KMT2AMEN1POLBALDH1A1KDM4E | |
| SCHEMBL31083645 | 0.85 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL6318913 | 0.84 | ALDH1A1 (0.46) | KMT2AMEN1POLBMAPK1ALDH1A1 | |
| SCHEMBL652636 | 0.81 | HDAC8 (0.41) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL8567787 | 0.81 | MTNR1A (0.49) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL30576465 | 0.81 | MTNR1A (0.49) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL8567784 | 0.81 | MTNR1A (0.49) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL431522 | 0.81 | MTNR1A (0.49) | KMT2AMEN1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |