Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863594 | 0.81 | RXFP1 (0.59) | SIGMAR1RXFP1HSP90AA1HRH4HRH3 | |
| SCHEMBL6807257 | 0.80 | NPC1 (0.69) | SIGMAR1RXFP1HSP90AA1HRH4HRH3 | |
| SCHEMBL30417397 | 0.80 | RXFP1 (0.68) | SIGMAR1RXFP1HSP90AA1HRH4HRH3 | |
| SCHEMBL12522808 | 0.80 | RXFP1 (0.68) | SIGMAR1RXFP1HSP90AA1HRH4HRH3 | |
| SCHEMBL937500 | 0.80 | LMNA (0.71) | SIGMAR1RXFP1HRH4HPGDLMNA | |
| SCHEMBL8570079 | 0.76 | TSHR (0.54) | HRH4HPGDLMNAPOLBNPC1 | |
| SCHEMBL8358286 | 0.76 | SIGMAR1 (0.76) | SIGMAR1HPGDLMNA | |
| SCHEMBL8253848 | 0.75 | RXFP1 (0.77) | SIGMAR1RXFP1HSP90AA1HRH4HRH3 | |
| SCHEMBL7245767 | 0.74 | GNE (0.62) | SIGMAR1RXFP1HRH4HRH3LMNA | |
| SCHEMBL8358137 | 0.74 | SIGMAR1 (0.81) | SIGMAR1RXFP1HPGDMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773236-A | FLUORESCENT DYES FOR DETECTION OF ENZYMES FOR METABOLISM IN CELLS | MOLECULE PROBES, INC. (US) | 1998-06-30 | — | — | US | disclosed |