Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GABRD | O14764 | 1/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.57 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3584183 | 0.95 | SIGMAR1 (0.69) | SIGMAR1ALDH1A1GABRDGABRA1GABRB1 | |
| SCHEMBL20267190 | 0.93 | SIGMAR1 (0.72) | SIGMAR1ALDH1A1TP53GABRDGABRA1 | |
| SCHEMBL4709504 | 0.92 | SIGMAR1 (0.65) | SIGMAR1ALDH1A1TP53GABRDGABRA1 | |
| Hydrochloric Acid SCHEMBL30444118 | 0.92 | SIGMAR1 (0.70) | SIGMAR1ALDH1A1TP53GABRDGABRA1 | |
| SCHEMBL7252122 | 0.90 | SIGMAR1 (0.67) | SIGMAR1ALDH1A1TP53GABRDGABRA1 | |
| SCHEMBL2336862 | 0.88 | SMN1; SMN2 (0.71) | SIGMAR1ALDH1A1USP2LMNAMAPK1 | |
| SCHEMBL2733887 | 0.88 | SIGMAR1 (0.65) | SIGMAR1ALDH1A1L3MBTL1 | |
| SCHEMBL14107680 | 0.88 | SIGMAR1 (0.65) | SIGMAR1ALDH1A1TP53GABRDGABRA1 | |
| SCHEMBL8355984 | 0.88 | SIGMAR1 (0.65) | SIGMAR1ALDH1A1TP53GABRDGABRA1 | |
| SCHEMBL10070452 | 0.88 | ALDH1A1 (0.78) | SIGMAR1ALDH1A1TP53HPGDL3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922203-A | AMINE COMPOUND REACTED WITH ACYL HALIDE FOR MEMBRANES | HYDRANAUTICS (US) | 1999-07-13 | — | — | US | claimed |
| US-4613878-A | DECOLORIZING AGENT COMPRISING AROMATIC DIAMIDE OR PIPERAZINE DERIVATIVE, HAVING TWO ACYLAMINO GROUPS | RICOH COMPANY, LTD. (JP) | 1986-09-23 | — | — | US | disclosed |