SCHEMBL8569104

SCHEMBL8569104

CCc1cc2c(cc1[N+](=O)[O-])-c1c(cc([N+](=O)[O-])cc1[N+](=O)[O-])C2=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 1/20 0.50
HTT P42858 2/20 0.41
POLB P06746 1/20 0.41
S100A4 P26447 3/20 0.40
TRPV1 Q8NER1 1/20 0.40
ALDH1A1 P00352 4/20 0.40
CYP1A2 P05177 4/20 0.40
HIF1A Q16665 3/20 0.40
HSD17B10 Q99714 3/20 0.40
CYP2C9 P11712 2/20 0.40
MAPK1 P28482 2/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
STAT6 P42226 1/20 0.40
PHLPP2 Q6ZVD8 1/20 0.40
PTPRC P08575 2/20 0.39
HPRT1 P00492 1/20 0.39
KDM4E B2RXH2 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3207925 0.86 HKDC1 (0.55) HKDC1S100A4TRPV1ALDH1A1CYP1A2
SCHEMBL8988676 0.84 HTT (0.41) HKDC1HTTPOLBALDH1A1CYP1A2
SCHEMBL12520177 0.82 HKDC1 (0.52) HKDC1S100A4TRPV1ALDH1A1CYP1A2
SCHEMBL29435119 0.79 HKDC1 (0.65) HKDC1S100A4TRPV1ALDH1A1CYP1A2
SCHEMBL74588 0.79 HKDC1 (0.65) HKDC1S100A4TRPV1ALDH1A1CYP1A2
SCHEMBL29413355 0.77 S100A4 (0.62) HKDC1S100A4TRPV1ALDH1A1CYP1A2
SCHEMBL28968859 0.77 ALDH1A1 (0.67) HTTPOLBS100A4ALDH1A1CYP1A2
SCHEMBL55362 0.77 S100A4 (0.62) HKDC1S100A4TRPV1ALDH1A1CYP1A2
SCHEMBL6924564 0.77 PTPRC (0.58) HKDC1S100A4TRPV1ALDH1A1CYP1A2
SCHEMBL8573732 0.76 HSP90AA1 (0.53) HKDC1HTTPOLBALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5705694-A Trinitrofluoroenonimine derivative and electrophotosensitive material using the same MITA INDUSTRIAL CO., LTD. (JP) 1998-01-06 US disclosed
EP-0716078-A1 2-Ethyl-3,5,7-trinitrofluorenonimine derivative and use as charge transport MITA INDUSTRIAL CO. LTD. (JP) 1996-06-12 EP disclosed