Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.47 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569152 | 0.84 | CCR3 (0.46) | CCR3MEN1KMT2ALMNAGAA | |
| Maleic Acid SCHEMBL8569150 | 0.74 | CCR3 (0.55) | CCR3MEN1KMT2AGAAKDM4E | |
| Fumaric Acid SCHEMBL8569153 | 0.74 | CCR3 (0.55) | CCR3MEN1KMT2AGAAKDM4E | |
| SCHEMBL27420015 | 0.72 | HCAR2 (0.49) | CCR3HCAR2SIGMAR1 | |
| SCHEMBL7253377 | 0.70 | CCR3 (0.63) | CCR3PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL28750865 | 0.69 | SLC18A3 (0.67) | CCR3PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL28834672 | 0.69 | TMEM97 (0.63) | CCR3PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL5969423 | 0.69 | CCR3 (0.67) | CCR3PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL16218991 | 0.69 | ALDH1A1 (0.66) | MEN1KMT2ALMNAGAAKDM4E | |
| Fumaric Acid SCHEMBL9253101 | 0.69 | CCR3 (0.60) | CCR3MEN1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760234-A | THERAPY FOR NERVOUS SYSTEM DISORDERS | NEUROGEN CORPORATION (US) | 1998-06-02 | — | — | US | claimed |