Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrole SCHEMBL8569144 | 0.84 | CCR3 (0.47) | CCR3GAALMNATMEM97SIGMAR1 | |
| SCHEMBL16218991 | 0.69 | ALDH1A1 (0.66) | GAALMNAL3MBTL1RAB9AMEN1 | |
| SCHEMBL4023997 | 0.69 | GRIN2B (0.66) | CCR3GAALMNAGRIN2DGRIN3B | |
| SCHEMBL8362502 | 0.69 | CCR3 (0.65) | CCR3TMEM97SIGMAR1MEN1KMT2A | |
| SCHEMBL4826474 | 0.69 | LMNA (0.51) | CCR3GAALMNAL3MBTL1RAB9A | |
| SCHEMBL6996302 | 0.68 | GRIN1 (0.61) | CCR3LMNAGRIN2DGRIN3BADRA1D | |
| Hydrochloric Acid SCHEMBL1373308 | 0.68 | GRIN2D (0.64) | CCR3LMNAGRIN2DGRIN3BADRA1D | |
| SCHEMBL7253377 | 0.67 | CCR3 (0.63) | CCR3MEN1KMT2A | |
| SCHEMBL4578817 | 0.67 | L3MBTL1 (0.64) | LMNAL3MBTL1GRIN2DGRIN3BADRA1D | |
| SCHEMBL28834672 | 0.67 | TMEM97 (0.63) | CCR3GAATMEM97SIGMAR1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760234-A | THERAPY FOR NERVOUS SYSTEM DISORDERS | NEUROGEN CORPORATION (US) | 1998-06-02 | — | — | US | claimed |