Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936411 | 0.88 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1PIN1MEN1 | |
| SCHEMBL2771800 | 0.86 | MAPT (0.48) | CYP11B1CYP11B2CYP19A1MEN1KMT2A | |
| SCHEMBL2772158 | 0.86 | MEN1 (0.48) | CYP11B1CYP11B2CYP19A1PIN1MEN1 | |
| SCHEMBL14988733 | 0.82 | RAB9A (0.60) | CYP11B1CYP11B2CYP19A1MEN1KMT2A | |
| SCHEMBL14988688 | 0.81 | RAB9A (0.57) | CYP11B1CYP11B2CYP19A1MEN1KMT2A | |
| SCHEMBL2305236 | 0.81 | NPC1 (0.68) | PIN1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL30015078 | 0.81 | NPC1 (0.68) | PIN1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28087330 | 0.78 | ALDH1A1 (0.50) | CYP11B1CYP11B2MEN1KMT2ARAB9A | |
| SCHEMBL3585058 | 0.78 | MGMT (0.52) | CYP11B1CYP11B2CYP19A1PIN1MEN1 | |
| SCHEMBL8316270 | 0.78 | MEN1 (0.55) | CYP11B1CYP11B2CYP19A1PIN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |