Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14291861 | 0.75 | ALDH1A1 (0.45) | KMT2AHPGDALDH1A1MEN1SRD5A2 | |
| SCHEMBL8570794 | 0.74 | ADORA3 (0.62) | KMT2AALDH1A1MEN1KDM4EPTGDR2 | |
| SCHEMBL1081516 | 0.66 | CYP1A2 (0.52) | KMT2AHPGDALDH1A1MEN1NPC1 | |
| Benzophenone SCHEMBL8820654 | 0.65 | AKR1B1 (0.77) | KMT2AHPGDALDH1A1AKR1B1SRD5A2 | |
| SCHEMBL9865683 | 0.65 | CYP1A2 (0.50) | KMT2AHPGDALDH1A1MEN1NPC1 | |
| SCHEMBL1415906 | 0.64 | SRD5A2 (0.73) | KMT2AHPGDALDH1A1MEN1AKR1B1 | |
| Benzophenone SCHEMBL30537001 | 0.62 | ALDH1A1 (1.00) | KMT2AHPGDALDH1A1MEN1SRD5A2 | |
| Benzophenone SCHEMBL30536983 | 0.62 | ALDH1A1 (1.00) | KMT2AHPGDALDH1A1MEN1SRD5A2 | |
| Benzophenone SCHEMBL1074283 | 0.62 | ALDH1A1 (1.00) | KMT2AHPGDALDH1A1MEN1SRD5A2 | |
| Benzophenone SCHEMBL6061130 | 0.62 | ALDH1A1 (1.00) | KMT2AHPGDALDH1A1MEN1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705650-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| US-5585494-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO. LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0536900-A2 | Process for preparing 1,2,4-Thiadiazole Derivatives | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1993-04-14 | — | — | EP | disclosed |