Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569337 | 1.00 | NAMPT (0.41) | NAMPTP2RX7 | |
| SCHEMBL8566511 | 0.78 | ALDH1A1 (0.45) | NAMPT | |
| SCHEMBL8569344 | 0.73 | HRH4 (0.43) | NAMPTP2RX7 | |
| SCHEMBL9777091 | 0.71 | HRH4 (0.32) | — | |
| SCHEMBL9777093 | 0.71 | HRH4 (0.32) | — | |
| SCHEMBL11801567 | 0.68 | — | — | |
| SCHEMBL11801557 | 0.68 | — | — | |
| SCHEMBL11467208 | 0.67 | MIF (0.39) | NAMPT | |
| SCHEMBL8375655 | 0.67 | P2RX7 (0.54) | NAMPTP2RX7 | |
| SCHEMBL27357155 | 0.65 | GRIN1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431943-B1 | Spiro(pyran)piperidine derivatives | MERCK & CO INC (US) | 1998-07-15 | — | — | EP | disclosed |
| US-5633247-A | ANTIARRTHYMIA AGENT | MERCK & CO., INC. (US) | 1997-05-27 | — | — | US | disclosed |
| US-5206240-A | Antiarrhythmia agents | MERCK & CO., INC. (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0431943-A2 | Nitrogen-containing spirocycles | MERCK & CO. INC. (US) | 1991-06-12 | — | — | EP | disclosed |