Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569422 | 0.74 | SMN1; SMN2 (0.51) | MEN1KMT2ASMN1; SMN2BCAT2ALDH1A1 | |
| SCHEMBL5883327 | 0.73 | TACR1 (0.54) | TACR1MEN1KMT2ASMN1; SMN2BCAT2 | |
| SCHEMBL7452209 | 0.73 | TACR1 (0.46) | TACR1MEN1KMT2ASMN1; SMN2HSD17B1 | |
| SCHEMBL8574900 | 0.72 | TACR1 (0.42) | TACR1MEN1KMT2ASMN1; SMN2HSD17B1 | |
| Hydrochloric Acid SCHEMBL5883686 | 0.72 | TACR1 (0.52) | TACR1MEN1KMT2ASMN1; SMN2BCAT2 | |
| SCHEMBL8570029 | 0.71 | KDM4E (0.40) | TACR1MEN1KMT2ASMN1; SMN2HSD17B1 | |
| SCHEMBL31393815 | 0.71 | TACR1 (0.51) | TACR1MEN1KMT2ASMN1; SMN2BCAT2 | |
| SCHEMBL8574194 | 0.70 | TACR1 (0.43) | TACR1MEN1KMT2ASMN1; SMN2HSD17B1 | |
| SCHEMBL8569641 | 0.70 | MEN1 (0.47) | TACR1MEN1KMT2ASMN1; SMN2HSD17B1 | |
| SCHEMBL7409011 | 0.70 | KMT2A (0.45) | TACR1MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |