Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6277246 | 0.76 | GPR35 (0.49) | SMN1; SMN2MEN1KMT2AHPGDNPC1 | |
| SCHEMBL8569426 | 0.74 | TACR1 (0.42) | SMN1; SMN2MEN1KMT2ARXFP1HPGD | |
| SCHEMBL7445918 | 0.73 | MEN1 (0.86) | SMN1; SMN2MEN1KMT2AHPGDNPC1 | |
| Hydrogen Sulfide SCHEMBL28029146 | 0.71 | MEN1 (0.83) | SMN1; SMN2MEN1KMT2AHPGDNPC1 | |
| SCHEMBL3760398 | 0.70 | MEN1 (0.74) | SMN1; SMN2MEN1KMT2ARXFP1HPGD | |
| SCHEMBL12261074 | 0.69 | ESR1 (0.38) | SMN1; SMN2MEN1KMT2ARXFP1HPGD | |
| SCHEMBL12261073 | 0.69 | GPR35 (0.42) | SMN1; SMN2NPC1HTR2CALDH1A1TP53 | |
| SCHEMBL30463435 | 0.69 | MEN1 (1.00) | SMN1; SMN2MEN1KMT2ABCAT2ALDH1A1 | |
| SCHEMBL6677412 | 0.69 | MEN1 (1.00) | SMN1; SMN2MEN1KMT2ABCAT2ALDH1A1 | |
| SCHEMBL8574893 | 0.68 | MEN1 (0.51) | SMN1; SMN2MEN1KMT2ARXFP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |