Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464748 | 0.83 | OPRM1 (0.64) | OPRL1OPRM1OPRK1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL11729597 | 0.81 | OPRL1 (0.62) | OPRL1OPRM1OPRK1MAOAMAOB | |
| SCHEMBL8887951 | 0.79 | OPRM1 (0.41) | OPRL1OPRM1OPRK1MAOAMAOB | |
| SCHEMBL10703927 | 0.78 | MAOA (0.48) | OPRL1OPRM1OPRK1MAOAMAOB | |
| SCHEMBL27353384 | 0.74 | OPRM1 (0.40) | OPRL1OPRM1OPRK1MEN1ALDH1A1 | |
| SCHEMBL9833979 | 0.73 | KMT2A (0.48) | OPRL1OPRM1OPRK1MEN1ALDH1A1 | |
| SCHEMBL14601364 | 0.72 | OPRM1 (0.76) | OPRL1OPRM1OPRK1MAOAMAOB | |
| SCHEMBL10625075 | 0.72 | TSHR (0.41) | OPRL1OPRM1MAOAMAOBSLC6A2 | |
| SCHEMBL28128001 | 0.72 | OPRL1 (0.44) | OPRL1OPRM1OPRK1MAOAMAOB | |
| SCHEMBL18114517 | 0.72 | MAOA (0.45) | OPRL1OPRM1OPRK1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705674-A | Process for preparing ortho-nitrobenzonitriles | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-06 | — | — | US | disclosed |
| US-5510528-A | Preparation of halomethylbenzoly cyanides and novel halomethylbenzoyl cyanides | BASF AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |
| US-5446199-A | Preparation of halomethylbenzoyl cyanides and novel halomethylbenzoyl cyanides | BASF AKTIENGESELLSCHAFT (DE) | 1995-08-29 | — | — | US | disclosed |