Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464748 | 0.78 | OPRM1 (0.64) | KMT2AALDH1A1OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL11729597 | 0.76 | OPRL1 (0.62) | KMT2AOPRM1OPRL1OPRK1 | |
| SCHEMBL27699362 | 0.73 | OPRL1 (0.54) | KMT2AMEN1ALDH1A1OPRM1OPRL1 | |
| SCHEMBL8569481 | 0.73 | OPRL1 (0.46) | KMT2AMEN1ALDH1A1POLBOPRM1 | |
| SCHEMBL10703927 | 0.73 | MAOA (0.48) | ALDH1A1OPRM1OPRL1OPRK1ADRB2 | |
| SCHEMBL27353384 | 0.72 | OPRM1 (0.40) | KMT2AMEN1ALDH1A1POLBOPRM1 | |
| SCHEMBL8887951 | 0.71 | OPRM1 (0.41) | KMT2AMEN1ALDH1A1POLBOPRM1 | |
| SCHEMBL28128001 | 0.71 | OPRL1 (0.44) | KMT2AMEN1ALDH1A1POLBOPRM1 | |
| Cyclohexane SCHEMBL9835197 | 0.69 | ALOX5 (0.64) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL3619221 | 0.69 | ADRB2 (0.47) | KMT2AMEN1ALDH1A1ADRB2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200377-B1 | HYDROXAMATES | SQUIBB & SONS INC (US) | 1991-10-09 | — | — | EP | claimed |
| EP-0200377-A2 | Hydroxamates | E.R. Squibb & Sons, Inc. (US) | 1986-11-05 | — | — | EP | claimed |
| US-4604407-A | Hydroxamates | E. R. SQUIBB & SONS, INC. (US) | 1986-08-05 | — | — | US | claimed |
| EP-0200377-B1 | HYDROXAMATES | SQUIBB & SONS INC (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0200377-A2 | Hydroxamates | E.R. Squibb & Sons, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4604407-A | Hydroxamates | E. R. SQUIBB & SONS, INC. (US) | 1986-08-05 | — | — | US | disclosed |