Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553897 | 0.89 | GAA (0.54) | GAAKMT2APKMTSHRRNASEH1 | |
| SCHEMBL6951808 | 0.87 | GAA (0.53) | GAAKMT2APKMTSHRRNASEH1 | |
| Hydrochloric Acid SCHEMBL8569715 | 0.87 | GAA (0.53) | GAAKMT2APKMTSHRRNASEH1 | |
| SCHEMBL6950138 | 0.84 | KMT2A (0.49) | GAAKMT2APKMTSHRRNASEH1 | |
| SCHEMBL1552358 | 0.83 | RNASEH1 (0.54) | GAAKMT2APKMTSHRRNASEH1 | |
| SCHEMBL6840239 | 0.81 | KDM4C (0.54) | GAAKMT2APKMSMN1; SMN2PDE5A | |
| SCHEMBL6840255 | 0.80 | KDM5B (0.46) | GAAKMT2APKMTSHRRNASEH1 | |
| SCHEMBL9540475 | 0.78 | GAA (0.58) | GAAKMT2APKMTSHRRNASEH1 | |
| SCHEMBL8771674 | 0.78 | GAA (0.58) | GAAKMT2APKMTSHRPNP | |
| SCHEMBL1553712 | 0.78 | PDE4A (0.64) | GAAKMT2APKMTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |