Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 2/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946477 | 0.88 | RAB9A (0.50) | GAASMN1; SMN2RNASEH1HDAC3HDAC4 | |
| SCHEMBL1553897 | 0.86 | GAA (0.54) | KMT2AGAAPKMSMN1; SMN2TSHR | |
| SCHEMBL6951808 | 0.85 | GAA (0.53) | KMT2AGAAPKMSMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL8569715 | 0.85 | GAA (0.53) | KMT2AGAAPKMSMN1; SMN2TSHR | |
| SCHEMBL8569705 | 0.84 | GAA (0.51) | KMT2AGAAPKMSMN1; SMN2TSHR | |
| SCHEMBL1552358 | 0.83 | RNASEH1 (0.54) | KMT2AGAAPKMSMN1; SMN2TSHR | |
| SCHEMBL6946442 | 0.79 | GRIN2B (0.49) | GAAPKMSMN1; SMN2TSHRRNASEH1 | |
| SCHEMBL8576516 | 0.78 | GAA (0.51) | KMT2AGAAPKMSMN1; SMN2TSHR | |
| SCHEMBL6840255 | 0.77 | KDM5B (0.46) | KMT2AGAAPKMSMN1; SMN2TSHR | |
| SCHEMBL6948946 | 0.77 | NPC1 (0.46) | GAASMN1; SMN2RNASEH1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |