Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.69 |
| ▸ | AGTR1 | P30556 | 6/20 | 0.60 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214999 | 0.89 | AGTR1 (0.65) | GP6AGTR1AGTR2 | |
| SCHEMBL24360485 | 0.86 | GP6 (0.67) | GP6AGTR1AGTR2 | |
| SCHEMBL33 | 0.85 | AGTR1 (0.75) | GP6AGTR1AGTR2 | |
| SCHEMBL1014 | 0.85 | GP6 (0.66) | GP6AGTR1AGTR2 | |
| SCHEMBL8568897 | 0.84 | AGTR1 (0.59) | GP6AGTR1AGTR2 | |
| SCHEMBL965839 | 0.84 | AGTR1 (0.67) | GP6AGTR1AGTR2 | |
| SCHEMBL1459519 | 0.84 | GP6 (0.65) | GP6AGTR1AGTR2 | |
| SCHEMBL1457880 | 0.84 | GP6 (0.65) | GP6AGTR1AGTR2 | |
| SCHEMBL8565334 | 0.83 | AGTR1 (0.73) | AGTR1AGTR2 | |
| SCHEMBL359 | 0.82 | GP6 (0.63) | GP6AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649424-B1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | KNOLL AG (DE) | 1998-10-07 | — | — | EP | disclosed |
| US-5627191-A | Therapeutic agents | THE BOOTS COMPANY PLC (GB) | 1997-05-06 | — | — | US | disclosed |
| WO-1994001436-A1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | THE BOOTS COMPANY PLC (GB) | 1994-01-20 | — | — | WO | disclosed |