Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597788 | 0.82 | GSK3A (0.46) | MAPTEGFRLMNAMAPK1HPGD | |
| SCHEMBL8600079 | 0.80 | SMN1; SMN2 (0.47) | MAPTHTTEGFRLMNAMAPK1 | |
| SCHEMBL8563517 | 0.79 | MAPT (0.61) | MAPTHTTEGFRLMNAMAPK1 | |
| SCHEMBL8560819 | 0.79 | HPGD (0.53) | MAPTHPGD | |
| SCHEMBL28460390 | 0.78 | EGFR (0.55) | MAPTHTTEGFRLMNAMAPK1 | |
| SCHEMBL8568939 | 0.78 | VCAM1 (0.46) | MAPTHTTEGFRLMNAMAPK1 | |
| SCHEMBL8561208 | 0.77 | HPGD (0.43) | MAPTHTTLMNAMAPK1HPGD | |
| SCHEMBL8563024 | 0.76 | KMT2A (0.57) | MAPTHTTEGFRLMNAMAPK1 | |
| SCHEMBL8564301 | 0.75 | KDM4E (0.47) | MAPTHTTLMNAMAPK1HPGD | |
| SCHEMBL4926850 | 0.75 | MAPT (0.66) | MAPTHTTLMNAMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |