SCHEMBL8569835

SCHEMBL8569835

CC(C)(C)N1C(=O)C=C(c2ccccc2)C1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.49
ALDH1A1 P00352 3/20 0.49
NPSR1 Q6W5P4 3/20 0.49
GAA P10253 2/20 0.49
CCR6 P51684 2/20 0.49
HPGD P15428 2/20 0.49
ALOX12 P18054 2/20 0.49
CACNA1B Q00975 2/20 0.49
APBA1 Q02410 2/20 0.49
LMNA P02545 2/20 0.46
HTT P42858 1/20 0.46
CA12 O43570 2/20 0.44
CA9 Q16790 2/20 0.44
CA2 P00918 1/20 0.44
RGS4 P49798 1/20 0.43
HCRTR1 O43613 1/20 0.40
S1PR4 O95977 1/20 0.40
HSP90AA1 P07900 1/20 0.40
S1PR1 P21453 1/20 0.40
BACE1 P56817 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8566676 0.81 MAPT (0.49) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL149927 0.79 MAPT (0.53) MAPTALDH1A1NPSR1GAACCR6
Ethane SCHEMBL8564354 0.77 MAPT (0.51) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL8736161 0.74 MAPT (0.42) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL152254 0.72 MAPT (0.55) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL29644717 0.72 PTGS2 (0.44) MAPTALDH1A1NPSR1GAALMNA
SCHEMBL152799 0.71 MAPT (0.53) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL152219 0.71 MAPT (0.53) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL28770986 0.71 MAPT (0.53) MAPTALDH1A1NPSR1GAACCR6
SCHEMBL27519378 0.71 MAPT (0.53) MAPTALDH1A1NPSR1GAACCR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539266-A Maleimidocarbazole compound and synthesis method thereof 湘潭大学 2022-05-27 CN claimed
EP-0241260-B1 ACETOPHENONE BASED BISPHENOL POLYARYLATE RESIN COMPOSITIONS, THEIR FORMATION AND MOLDING ARCO Chemical Technology, L.P. (US) 1992-03-04 EP claimed
CN-114539266-A Maleimidocarbazole compound and synthesis method thereof 湘潭大学 2022-05-27 CN disclosed
US-5773630-A REACTION OF ANHYDRIDE WITH PRIMARY AMINE TO FORM CYCLIC IMIDE BAYER AKTIENGESELLSCHAFT (DE) 1998-06-30 US disclosed